Speaking to iFollow Iron ahead of the game, he said: "This week is all about bouncing back, it’s all we can do. We needed to get a good weeks training in and go again.
“It’s a long season there are lots of games so we are going to lose some, draw some and win hopefully. We just have to get on with it, our confidence is still high. Hopefully, we get three points on Saturday.”
Reflecting further, Spence said: “We’re going to hopefully go on a run but we’ll pick up defeats as well. It’s a young squad but I think we could beat anyone in the league. We just have to keep the confidence high.
“The negative from last week was I think we were on top in the game, going ahead with the goal. But we kind of changed that a bit and let them in a little.
“We should have tried to kill them off in the first half but it’s something we will try do this week.”
The team have been training hard this week ahead of the game against the U's, who are second in the league. Spence added: “Training has been good but intense. We’re all still hungry and we’ll put last week behind us.
“Cambridge is a good team; I’ve not played against them. I think it’s anybody’s league looking at the results. Every game is hard.”
Spence commented that the manager Neil Cox had been very supportive to the team. He said: “(he's told us to) just keep going. We’re only five games in and there’s still a long season ahead of us.”
Discussing Wednesday's Under-23s win against Huddersfield Town, he said: “It was a good result. It was good for the squad to win 4-0, especially with the four goals from four different scorers.
“We’re all one big team, we're all involved together but you can only pick 11 on a Saturday. Everybody’s going to get their chance and it’s a long season, like I've said before.
“There are going to be injuries and suspensions and everyone will have the opportunity to prove themselves.”
Spence arrived at the club from Scottish Premier League side Ross County in the summer and touched on his first few months in England: “I’m happy to be playing games and I'm enjoying my time down here so far. The boys and the coaching staff have made me feel welcome. But I’m hoping to get some better results.
“I think we’ve been a bit hot and cold, but it’s early in the season still. We just need to keep our head down and we’ve got a really good young squad. When we find the right balance, we’ll put teams away.”
See much more from Lewis Spence on iFollow Iron. Click here to subscribe.