The Iron will be looking to record back-to-back wins for the first time this season when they take on Salford City this Saturday at the Peninsula Stadium (3pm kick-off).
Scunthorpe come into the match on the back of a convincing 3-1 home win against high-flying Exeter City, making it back-to-back home wins for the first time since the turn of the year. United will be looking to claim their first three points on the road this season.
The Ammies come into the fixture following a positive 2-1 victory away at Mansfield Town in midweek, as they bounced back from their own disappointment of a 2-0 defeat at Northampton Town last weekend.
Manager Paul Hurst has confirmed there are no fresh injury news ahead of the encounter, with the squad coming through the encounter against Exeter City in midweek.
Jordan Hallam (ankle) is close to a return and featured for the Under-23s at Bottesford on Wednesday as did John McAtee (shoulder) and Jacob Bedeau (calf).
George Miller (quad strain) is back with Barnsley for assessment on his injury, while Andy Dales (calf) remains absent. Jordan Clarke is out following an appendix operation, although the latter two were both back on grass running on Monday.
The two sides have never met in their history, so Saturday will be the first-ever clash between United and the Ammies.
Had Scunthorpe progressed past Shrewsbury Town in last season's Emirates FA Cup, they would have met in Round Three, but the Shrews edged the encounter 1-0.
ELSEWHERE IN LEAGUE TWO
Exeter City v Plymouth Argyle (1pm)
Colchester United v Newport County (3pm)
Crawley Town v Swindon Town (3pm)
Forest Green Rovers v Crewe Alexandra (3pm)
Grimsby Town v Cheltenham Town (3pm)
Leyton Orient v Carlisle United (3pm)
Macclesfield Town v Bradford City (3pm)
Northampton Town v Cambridge United (3pm)
Port Vale v Oldham Athletic (3pm)
Stevenage v Morecambe (3pm)
Walsall v Mansfield Town (3pm)