The Iron received a bye to this stage of the competition, while the Holy Blues beat Stamford AFC 3-2 to secure a place in the final eight.
The tie will take place at the KAL Group Stadium, also known as he Northolme, with ticket details to be confirmed.
The two sides last met in pre-season with United running out 6-0 victors following goals from Jason Law, Michael Kelly, Cameron Wilson (two), Danny Elliott (penalty) and Danny Whitehall.
