The Iron will face Wolverhampton Wanderers' Under-21s and Lincoln City at Glanford Park in the Checkatrade Trophy group stages.
Scunthorpe are in Group H in this season's competition and learned their opponents ahead of the start of the season.
For the third successive campaign, United are at home for two out of the three games, hosting Wolves' U21s and the Imps at Glanford Park before travelling to Mansfield Town.
Scunthorpe United v Wolverhampton Wanderers
Tuesday 4th September 2018
Scunthorpe United v Lincoln City
Tuesday 9th October 2018
Mansfield Town v Scunthorpe United
Tuesday 13th November 2018
Tickets are on sale now for the home games, with prices as follows:
12th Man member's seats will be reserved for the game.
You can purchase tickets in person at the Glanford Park ticket office, by calling 01724 747670 or through visiting www.sufctickets.com.
As soon as we have ticket details for the group stage game away at Mansfield Town, we will release them.