Funso Ojo and Kevin van Veen make way for Sam Mantom and Duane Holmes, as the only alterations from the side that defeated Oxford United 1-0 at the weekend.
Neal Bishop, facing his hometown club, was named as skipper for the Iron.
TEAM LINE-UPS
Middlesbrough: Dimi, Roberts, Fry, Ayala, Fabio, Leadbitter, Forshaw, Baker, Traore, Tavernier, Fletcher.
Substitutes: Medias, Friend, Gibson, Downing, Wing, Assombalonga, Gusted.
Scunthorpe United: Gilks, Townsend, Wallace, Mantom, Madden, Morris, Bishop, Adelakun, Holmes, Sutton, McArdle.
Substitutes: Watson, Ojo, Hopper, Redmond, Goode, Burgess, Butroid.
