A youthful Under-23s side will take on Doncaster Rovers in the Central League at Cantley Park on Monday afternoon (2pm kick-off).
The game was switched from Bottesford Town’s Birkdale Park due to a waterlogged pitch.
Due to the first team being in action away at Swindon Town on Tuesday night, it impacts the availability of a number of players who took part in last week's Under-23s Premier League Cup game at Hull City, which ended in a 0-0 draw.
Scunthorpe previously took on Doncaster in the Central League earlier in the season, with Lewis Butroid scoring in a 1-1 draw in November.
You will be able to follow live Twitter coverage from Monday afternoon's match by clicking here.