The game was switched from Bottesford Town’s Birkdale Park due to a waterlogged pitch.
Due to the first team being in action away at Swindon Town on Tuesday night, it impacts the availability of a number of players who took part in last week's Under-23s Premier League Cup game at Hull City, which ended in a 0-0 draw.
A number of players from the Under-18s squad will be involved, and they had a free weekend following the postponement of their away encounter at Burton Albion.
Scunthorpe previously took on Doncaster in the Central League earlier in the season, with Lewis Butroid scoring in a 1-1 draw in November.
You will be able to follow live Twitter coverage from Monday afternoon's match by clicking here.
