The Iron will be seeking to get off to a good start in their Checkatrade Trophy group on Tuesday night when Sunderland Under-21s visit Glanford Park (7.45pm kick-off).
Derby matches against Grimsby Town (home) and Doncaster Rovers (away) follow in October, as United look to build on their decent start to the season in the league.
Confidence was understandably high following the 4-0 away success at Plymouth Argyle on Saturday, and the result pushed Graham Alexander's side into the top six of League One for the first time this season.
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Both Kevin van Veen and Jordan Clarke were on the substitutes' bench on Saturday following their returns from injury, and could well feature - with boss Alexander saying changes will be made ahead of the match to enable some players who haven't been as involved to get game time.
The Iron will also be without trio Luke Williams, Jonny Margetts and Kyle Wootton again, and they are still a few weeks away from being back in the team.
There are no other injury concerns following Saturday's win.
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Click here to see this week's list of games.