The Iron have been installed at 9/4 with Sky Bet to back up last weekend's league win and get their first three points on the road this season against Tranmere Rovers on Saturday.
The away side are currently priced at 23/10, while a draw is priced at 21/10.
The two sides haven't met at Prenton Park since December 2012 when the hosts won the game 1-0. Sky Bet have a repeat scoreline at 11/2, while United to take the points following a 1-0 victory is 7/1.
The last time Scunthorpe won at Tranmere was back in April 2007. It was 2-0 on the day, with a repeat of that scoreline offered at 14/1, while it is 17/2 for the hosts.
The match is the 58th meeting between the two sides, but there have only been 10 draws amongst them. Correct score group betting is offering a 1-1, 2-2 or 3-3 at 4/1, while it is 20/1 for both teams to score in both halves.
The Iron are 14/1 to win both halves of the game, while Tranmere are 7/1 to achieve that feat.
For more odds, click here and remember that every bet placed benefits the club financially.