Leigh Doughty will take charge of the Iron's home Leasing.com Trophy encounter against Manchester City Under-21s on Wednesday.
The Lancashire-based official will travel to the Sands Venue Stadium for his 19th game of the season and his 11th in Sky Bet League Two.
In what is Doughty's first-ever EFL season, the Iron had him in charge for his first-ever EFL match back in August at Cheltenham Town, showing two yellow cards as United lost 4-1.
He arrived in the EFL at the first time of asking following his promotion to the National List of Referees after just one campaign on the National League.
A PE teacher by profession, he began refereeing in 2007 and was handed the play-off semi-final between Salford City and Eastleigh in the National League last season.
His most recent game came at the weekend at the Stadium of Light as he oversaw the encounter between Sunderland and Lincoln City in Sky Bet League One, showing two cautions as the Black Cats ran out 3-1 winners.
Last season, he took charge of a total of 16 matches, 15 of which in the National League and one in the FA Cup, showing 38 yellow cards and two reds. So far in this campaign, he's taken charge of 18 games, showing 54 yellow cards and two reds.
On Wednesday, Leigh will be assisted by David Avent and Ian Dudley, while Daniel Middleton will assume the role of fourth official.
PREVIOUS SCUNTHORPE UNITED ENCOUNTERS
| DATE | COMP | MATCH | Y | R |
| Aug 10, 2019 | LG 2 | Cheltenham Town 4-1 Iron | 2 | 0 |
PREVIOUS MANCHESTER CITY UNDER-21s ENCOUNTERS
None