The Iron have been installed as 19/10 underdogs with Sky Bet to get back to winning ways and record victory over Crawley Town this weekend.
The home side are currently priced at 13/10 to take all three points at the People's Pension Stadium, while a draw is 23/10.
United were eliminated by Crawley at the first hurdle of this year's Emirates FA Cup back in November, with a 4-1 scoreline harsh on the away side following three late goals. Sky Bet have pricing at 66/1 for Scunthorpe to avenge the defeat with the same scoreline, while the Reds are 50/1 to repeat the feat.
The visit will be the Iron's fourth to Crawley, but they're yet to win on any of the previous three. For a slender 1-0 win to get the first out of the way is 9/1, while a 2-1 win is 10/1.
Scunthorpe failed to score in midweek for the first time in eight games in all competitions and for the first time in 12 away games in all competitions, while United's last clean sheet away from home was on New Year's Day. Both teams to score is odds on 4/6, while both teams to score in both halves is 9/1.
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