The Iron have been installed as 19/20 odds-on favourites with Sky Bet to make it back-to-back wins and record victory over Cambridge United on Tuesday.
The away side are currently priced at 13/5 to take all three points at the Sands Venue Stadium, while a draw is 12/5.
United were defeated by the Us back in August 3-2 in what was a competitive game, with the Iron playing with ten men for over 70 minutes. A repeat score for the visitors is priced at 40/1, while the Iron to take their revenge with a mirrored scoreline from the reverse fixture is 28/1.
There are two price boosts available with Sky Bet, with Scunthorpe to win and both teams to score now at 10/3, while Cambridge to win and both teams to score is now 7/1.
John McAtee was the first and last goalscorer at the weekend in the 1-0 win over Cheltenham. He's priced at 5/1 to be the same on Tuesday, while he is 2/1 to score anytime. Liam O'Neil, a former loanee at Scunthorpe, scored the only goal in Cambridge's win at Newport. He's 28/1 to be first or last goalscorer, while he's 10/1 to net anytime.
The Iron kept their first clean sheet since New Year's Day at the weekend. The side are 5/2 to win to nil once more, while the Us are 6/1 to win to nil themselves.
For more odds, click here and remember that every bet placed benefits the club financially.