Iron manager Neil Cox has made five changes from the midweek encounter against Colchester United.
Jacob Bedeau, Ryan Loft, Abo Eisa, Jai Rowe and John McAtee come into the side, while Harrison McGahey, Aaron Jarvis, Devarn Green, Jordan Clarke and Jake Taylor coming out of the side.
SOUTHEND: Oxley, Bwonomo, McCormack, Hobson, Olayinka, Dieng, Akinola, Clifford, Acquah, Demetriou, Hart.
SOUTHEND SUBS: Seaden, Goodship, Egbri, Taylor, Klass, Kyprianou, Taylor.
IRON: Howard, Bedeau, Onariase, Gilliead, Loft, Eisa, Spence, Beestin, Rowe, O'Malley, McAtee.
IRON SUBS: Watson, Green, Hippolyte, Hallam, Jarvis, Cordner, Taylor.