Six Iron players were handed league debuts for the away clash at Coventry City.
Cameron Borthwick-Jackson, James Perch, James Horsfield, Olufela Olomola, Steven Humphrys and Andy Dales all lined up for their first starts in League One for United.
Meanwhile, Lee Novak was handed the skipper’s armband.
Elsewhere, Friday’s new arrivals Matthew Lund and George Thomas were named on the substitutes' bench.
Coventry City: O'Brien, Mason, Willis, Doyle, Biamou, Hiwula, Hyam, Ogogo, Sterling, Bayliss, Andreu.
Substitutes: Addai, Grimmer, Brown, Clarke-Harris, Ponticelli, Shipley, Thompson.
Scunthorpe United: Watson, Clarke, Borthwick-Jackson, Horsfield, Humphrys, Dales, Perch, Novak, Goode, Burgess, Olomola.
Substitutes: Flatt, Ojo, Lund, Thomas, Holmes, Wootton, Butroid.