Alexander highlighted the strength of Karl Robinson’s side, but the United boss is more than confident of getting a positive result, and also building on Saturday’s performance against Fleetwood Town.
Speaking to The Iron PlayerHD, Alexander said: “It’ll be a tough game. Charlton have got a lot of very good players within their squad. We have to go down there focusing on ourselves, and take the game to Charlton.
“We’re looking forward to getting down there - the lads are desperate for another game.
“They recruited well in the summer.
“Of course they lost Ademola Lookman to Everton, but they’ve still got many good players within their ranks - especially attacking wise.
“We have to be wary of that threat, but I believe if we play like we did on Saturday, we’re a match for anyone in this division.”
Despite being edged out by the Cod Army at Glanford Park, Alexander feels there was plenty to be taken from the display.
“I was pleased with our performance on Saturday, and of course there’s a disappointment in not getting the result, but the performance gave us all a lot of optimism,” he stated.
“We played very well, and we should have got something out of the game if we’re honest.
“We created some very good chances, so we have to keep on ploughing through and make sure we do everything we can to win the game.”
On the injury front, Alexander revealed Sam Mantom will once again miss out due to a groin problem, and added that the midfielder hasn't trained in the lead up to the game.
Mantom will be the only player unavailable to the Scunthorpe manager though, with Alexander declaring he has almost a full squad to choose from.
“Sam hasn’t trained, so he’s not involved with the squad - everyone else is,” Alexander revealed.
“We’ll travel down with the squad and we’ll pick the team which we feel can cause the most problems to Charlton.
“We’re slowly getting that rustiness out of a couple of the individuals, and they’re finding their feet again.
“This combination of games coming up will help them gain their full match fitness and let them show what they can do.”
See much more from Graham Alexander and Jordan Clarke on The Iron PlayerHD.