The Iron are 21/10 with Sky Bet to see off the threat of Rochdale and register a first league win of the season on Saturday.
The Dale are 5/4, while a draw can be backed at 12/5 with our official online betting partners.
United defeated Keith Hill's side 2-1 at Glanford Park in the most recent match between the two sides last season, and we are 10/1 to win by that margin once again.
You can also bet on the first goalscorer, with Paddy Madden the Scunthorpe favourite at 9/2. If you fancy an outside bet, Sam Mantom is available at odds of 14/1.
For more great odds ahead of the game, visit www.skybet.com/scunthorpe and remember that every bet placed via this method benefits the club financially.