The Iron will be looking to bounce back and end the campaign on a high by sealing survival with a win in the final league game of the 2018/19 season away at Plymouth Argyle on Saturday 4th May (5:30pm kick-off).
United go into the match on the back of 3-2 defeat to Bradford City at Glanford Park last time out, but will be searching to turn a positive second half performance into three points on Saturday.
However, the defeat against the Bantams, saw Scunthorpe slip to 23rd in the league table on goal difference, leaving the Iron needing a victory this weekend at Home Park, aligned with Walsall and Southend not winning, as they look to avoid relegation to League Two.
As for Plymouth, they parted ways with manager Derek Adams this week, following their fifth defeat in a row. Kevin Nancekivell has taken over in temporary charge.
Adams' final game as manager saw the Pilgrims lose heavily to Accrington Stanley last Saturday in a 5-1 defeat. That also left Plymouth in the relegation zone in 21st.
Right-back Tony McMahon continues to miss out with a hamstring injury picked up at Shrewsbury four weeks ago.
Funso Ojo went off with concession last weekend and will be assessed ahead of Saturday.
Jordan Clarke (knee) is back on the training pitch but won't return to action until pre-season.
Elsewhere, Ryan Colclough (knee) is out for the remainder of the season. Rory Watson (arm) is back on the training pitch too but is working towards a return at the start of pre-season in his recovery.
Caretaker manager Andy Dawson - click here to read
Attacker Adam Hammill - click here to read
Defender Byron Webster - click here to read
The Iron have a good record against the Pilgrims of late, only losing one of their last six matches against them.
That only defeat came in the reverse fixture at Glanford Park earlier this season, where Plymouth were 4-1 winners. Before that, United were on a five-match winning streak against the Pilgrims, in a run that stretched back to October 2009.
|2018-19 - Sat Oct 27||LG 1||Iron 1-4 Plymouth||Novak|
|2017-18 - Tue May 1||LG 1||Iron 2-0 Plymouth||Adelakun, Toney|
|2017-18 - Sat Aug 26||LG 1||Plymouth 0-4 Iron||Madden 2, Hopper, Morris|
|2013-14 - Sat Mar 15||LG 2||Plymouth 0-2 Iron||Syers, Cole og|
|2013-14 - Sat Sep 21||LG 2||Iron 1-0 Plymouth||Esajas|
|2009-10 - Sat Mar 20||CHAMP||Iron 2-1 Plymouth||Thompson, Woolford|
|2009-10 - Sat Oct 3||CHAMP||Plymouth 2-1 Iron||Hooper|
|2007-08 - Tue Mar 11||CHAMP||Iron 1-0 Plymouth||Morris|
|2007-08 - Sat Dec 1||CHAMP||Plymouth 3-0 Iron|
|2001-02 - Tue Jan 22||DIV 3||Plymouth 2-1 Iron||Carruthers|
|2001-02 - Sat Dec 22||DIV 3||Iron 2-1 Plymouth||Hodges|
|2000-01 - Sat Mar 17||DIV 3||Iron 4-1 Plymouth||Garcia, Torpey, Quailey 2|
|2000-01 - Tue Oct 17||DIV 3||Plymouth 1-0 Iron|
|1998-99 - Tue Mar 30||DIV 3||Plymouth 5-0 Iron|
|1998-99 - Sat Aug 29||DIV 3||Iron 0-2 Plymouth|
|1995-96 - Sat Feb 10||DIV 3||Iron 1-1 Plymouth||McFarlane|
|1995-96 - Tue Jan 23||DIV 3||Plymouth 1-3 Iron||Hope, Turnbull, McFarlane|
|1983-84 - Sat Apr 7||DIV 3||Iron 3-0 Plymouth||Bell, Brolly, Cammack|
|1983-84 - Tue Sep 27||DIV 3||Plymouth 4-0 Iron|
|1972-73 - Tue Feb 6||DIV 3||Plymouth 3-0 Iron|
|1972-73 - Tue Oct 10||DIV 3||Iron 1-1 Plymouth||Kirk|
|1963-64 - Sat Feb 29||DIV 2||Plymouth 3-1 Iron||Hodgson|
|1963-64 - Sat Nov 16||DIV 2||Iron 1-0 Plymouth||Neale|
|1962-63 - Sat Feb 23||DIV 2||Plymouth 2-3 Iron||McGuigan, Howells, Brownsword pen|
|1962-63 - Sat Oct 6||DIV 2||Iron 2-2 Plymouth||Godfrey, Hodgson|
|1961-62 - Sat Mar 31||DIV 2||Plymouth 3-1 Iron||Kaye|
|1961-62 - Sat Nov 11||DIV 2||Iron 5-1 Plymouth||Thomas 4, Thorpe|
|1960-61 - Sat Apr 22||DIV 2||Iron 2-0 Plymouth||Thomas, Bonson|
|1960-61 - Sat Dec 3||DIV 2||Plymouth 3-1 Iron||Sharpe|
|1959-60 - Thu Sep 3||DIV 2||Iron 2-0 Plymouth||Sharpe, Haigh|
|1959-60 - Mon Aug 24||DIV 2||Plymouth 4-0 Iron|
|SCUNTHORPE WINS||DRAWS||PLYMOUTH WINS|
ONE TO WATCH...
Striker Freddie Ladapo has been in fine form for the Pilgrims this season and has netted a total of 18 goals in 46 games.
Ladapo started his career with Colchester United, before leaving three years later to play in the National League for Kidderminster Harriers.
From there, he dropped further down the divisions to the Isthmian league where he joined Margate Town. However, his performances there in 2015/16 season saw him earn a trial with Premier League side Crystal Palace, which later turned into a two-and-a-half-year contract.
In 2018, the striker called time on his days at Selhurst Park and moved to Southend, before leaving for Plymouth on the South Coast, where he has caught the eye of many teams across the leagues ever since.
Now, this weekend, the 26-year-old will be looking to further add to his goalscoring tally, as he looks to end the season on a high as Plymouth's top scorer.
The Iron will be extra wary of the striker after he netted the opening goal in the Pilgrims 4-1 win over United back in October.
ELSEWHERE IN LEAGUE ONE...
Blackpool vs Gillingham
Bradford City vs AFC Wimbledon
Bristol Rovers vs Barnsley
Charlton Athletic vs Rochdale
Doncaster Rovers vs Coventry City
Luton Town vs Oxford United
Peterborough United vs Burton Albion
Portsmouth vs Accrington Stanley
Shrewsbury Town vs Walsall
Southend United vs Sunderland
Wycombe Wanderers vs Fleetwood Town