The Iron entered their away encounter at Leicester City making four changes from the side beaten 2-0 at West Bromwich Albion in midweek.
Debutant Michael Raynes replaced the suspended Cliff Byrne in defence, Marcus Williams returned from suspension to displace Brendan Moloney, with Matt Sparrow making way for Grant McCann and Paul Hayes coming in for Donal McDermott.
Joe Murphy started in goal, with the defence consisting of Raynes, David Mirfin, stand-in captain Rob Jones and Williams.
Michael O'Connor, Sam Togwell, Josh Wright and McCann formed the midfield, with Hayes supporting Gary Hooper in attack.
The substitutes were Josh Lillis, Andrew Wright, Ian Morris, Sparrow, Martyn Woolford, McDermott and Jonathan Forte.
TEAM LINE-UPS
Leicester City: Weale, Morrison, Brown, Oakley, King, Dyer, Berner, Waghorn, Wellens, Gallagher, Hobbs.
Substitutes: McGivern, Solano, HOward, Logan, N'Guessan, Kermorgant, Bruce.
Scunthorpe United: Murphy, Raynes, Mirfin, Jones, Williams, O'Connor, Togwell, J. Wright, McCann, Hayes, Hooper.
Substitutes: Lillis, A. Wright, Morris, Sparrow, Woolford, McDermott, Forte.
Referee: David Phillips.